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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ec3b44ef2dd7b4fb0066b24dc6c8b3f8711e06b31d959ff8ebada767eee9a8' 
  AND token = 'DjtsRW9b6U9zJkQiytuepJUJZiNsL9MRF4AmrN0yQpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}