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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e70e4481f186388661670442fb745ef3d9f32a7fd9e3f7d4c21a12ee702c14d' 
  AND token = '/dEBHLNnCjd0xAl+v4d9OoWDYuEX8c+RjgMQDCfe9eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}