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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64138c67435c0e877c473e9b87c54a10e08ffc74265e46e8c10095573bee0e4b' 
  AND token = 'zRksW//yEZ5OtlDvxz1T19K/kUxa8MYIgDsOaZ3S8Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}