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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579722e5cee1f9d6f55a9508a43319de1e48ec2ea0dd5eea03f9550b25d4cd46' 
  AND token = 'Gi2E9eXBXu5xdgd4c9XwR04O21BZkiYJCNnwu1uDA6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}