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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c888582ca649591ddc49ebd7e3db1aa8eb8c13edb9db357b8a320edd36af003e' 
  AND token = 'GlJcEr8IXmx/zdM1THpViSyyYcbFBC2RU+h+P2bJV84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}