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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05bc3da46e0460d64c1f94143df7592eedecad69ec80ab2036e4a75de3e6f1e8' 
  AND token = 'yC0jpXffDryqZmkLTMJYKlT8+7AJC1PTD0Mr/NrXZrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}