SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bb8c4afb028c6c9f9179cfbb65ced3e9362ec5bb338659d47cee517cdac6208' 
  AND token = 'Uu/0HXdX0bQA3nDCGlFDcFnbjmpDS5sy2Ln5gj0ee2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}