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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c91673a7b00f38228427b966d5a337b727f3542097716a6f61b162ecd94714e' 
  AND token = 'HrOyrEyJHNp7rEtwmo3AAm1OClOyvwi0Zy4kFBRTRYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}