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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e1d227311203a00f520f9ad6ea524f8533d89f8a1f8ee0e6f966df63480264' 
  AND token = 'rzOF07hD9imfNZLQUcYS7myEENQ6ftUg9xI9r2ImCDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}