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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '364572d645bd3bf3c506336c431f888e90f0a40736953170647cbc7a4e0a9cab' 
  AND token = 'DxUYvydYeV83FVn2neD7MT18Y2+lOvHcWKsEqdNn2Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}