SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fddfa5e73527ad7038d7e040a8aaeaffcb286e74016068b5476e72cc925aed3a' 
  AND token = 'S+Qd7sjoJ8E37J4zTVvBMNEonn3jgD02CtTCD45l0Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}