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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65db182549b7cb9d1dc6376a66f47f5bde340dae71d6780c83fe2797d4044a85' 
  AND token = '38en7+KOuYtev3DO1QAWbShR/fsmr9nV3yMYCliyiMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}