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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c7e72e61db8c05f7529f093ff77205ca2f10a2db50221dc48e7ebf56f275053' 
  AND token = '7smJxqGTL/Y8S0C6jAdAIIOnBv+OyoAwmD4kKF3zM0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}