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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7725be07e07cf2d78dd208608af5b80c0b1b5c22c9d9cbd328bad3e04fa05fe9' 
  AND token = 'Ls5XnHa2ARg9HZxp/K8MZmlcLRUsos5KJd9BPzHAWeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}