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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73def15741f3cf54814622b6b299d25af8ecfaed3f1635e483d59e8f0cd681a' 
  AND token = 'SlDouA0EksrY/0ESTcXKxk4xKmOxBlNWzvTlOYkdPWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}