SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9641e64832000fa18cacbe6189e72334d7207fe47b0da3e78253708ed269418' 
  AND token = 'ZOa1o7oE1cy5DoNAQLnkbRtYj7uBIKyNWbBcukyJ7D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}