SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e215f7271cea4de483da84b92b729537ce43866c96d66cf1cb9c112d1296ebd4' 
  AND token = 'BNo2gi/0/Uao8Uc5mp3rPGYPYs2j8WiIyVpRfavYYrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}