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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a376b754edebf25de6e293634d435345683bfd29454e0de30a0e4df849e2c677' 
  AND token = 'k3bznmq5BLr5jrQU2gXWOvUeFZ+irxBwzara2O9y3Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}