SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1345239ea65268e0627d98e4f3f8f77102a7e480814e9e004b0ff8558f23501c' 
  AND token = 'Q8bxk2IkfIvowyDCXL3uW9OIuHtf2bOeSy0xyLoPfRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}