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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf87ded39c052ad0acd3eed560fb138a4734a99baf7384a0f4a838fb8368a4c' 
  AND token = 'Nsw1EmnlDs94UDm+S6q1a5RMrDhZp4pDGrLNYvYt04s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}