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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151d7820fe83777caccac179274e996b0e7fe58f3d6f16fece3ead6fe2ad9878' 
  AND token = 'r8j0W4U1BrkA5GhfQU1qVpkj7o+tgMu9+mJRI4pOZAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}