SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d1ca42b0c2865e70f88e5a00169dc1008ded8994968857e26b04fb193c9a4e' 
  AND token = 'wBn7AaxVRZCJnzsE2EjazoCItEsWeWtWCGUk+wvnbc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}