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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd429cbd5ca33cdca567ea65231693ef87874a74c572aef78a81c7be4fe1bf6' 
  AND token = 'uueXPvS5QS8PAYqWsYLkoHlq8p5wALJYXpYd60N1DYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}