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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6443d667333f8b5e39210be930894ecb85f4a8bb1eb819f9ce445dd5c9da87' 
  AND token = '1c0cS3FVBrJmV/KHvc4s59tw8vClRAeuxMoviWZ73Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}