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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '326dedc9aedb2ec59c7e3a9c20b61cd6f2977fb8248a41f9b876e0555463fb29' 
  AND token = '+NhL3y951QLGpdtZaZaLk0HnErbcrsSZrA9oge21Y2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}