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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e142120597fc94fd7c8809bcd8c7bdb5c025ac19b485ce96d9eee4379d96c0d' 
  AND token = 'jS6Xm9uSGwQ6y+5dbrioKcJHOVHQqz65q4fzecxsUq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}