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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '015da63ab6eddad946282ad3fdace94415cfa13e0bbda76ca6d87b1435a66e37' 
  AND token = 'MGXlrjEhEskFBE2qWaSQo5rmzHyONudCTwAddqr2440=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}