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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ba2e815e19f304d1347094f1ce75d94dbd76b5623861012ab752f057e12b26' 
  AND token = 'O3fCOpLChAzt2R8Q9akOP6s1/M8eyasy6T6nZmWhWgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}