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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e236a78eebdee9fa0a814356817083a732b01366a896a76ba07110c573e6a0ad' 
  AND token = 'FWl+hEg3xPWVy8dxm1HyzYeBvwdZ5mF6XhlIk1Aj07E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}