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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ce7ff48afe3661e6e334dfb60c0ac8e7d5408ce974ecb4cf5a4056ecf65326' 
  AND token = 'TaH/ELDLcejyHiDchhvQ1W0C6phZPxxUCCs+YMlk8Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}