SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b226eeb4989968cda6a4155d23de5504ea3652224d6d030a86b1ac5cc32ac45' 
  AND token = 'iL1FXqcbAeX4wyiMkojc32HV+SnAieuQRnHWUB4U9t4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}