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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc9a0c70a10124cd85c0d7b675d3c0781e75dfff78e429719505bd3750018c20' 
  AND token = '84lXZanqJEpzom1laJWaG82oWHdhWN2vI8fU5HarQkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}