SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a70d880e5b92cd96455849f35aa7914c1005bb75beb7ee7f8b870255919de6c' 
  AND token = '3onpFT87lCvor/YunsU45GYMHFb87S5sK3zQQNhBOUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}