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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5578f43f4c79f49d0eaf05318f5e5a6b7abf01356d8c35477cdf63ea83dad78b' 
  AND token = '1vcTLplw1tCWUIhpbwSQgVszi5mUIKMwBCoZWUK8Cpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}