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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adaefb65cf64ed8ea6e48a0940deb6df12af076780edaf63de318c532f2607c' 
  AND token = 'wfxs2S3E6t5C4zUm0L/X1x101RS44N6iUpLKO8tU4sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}