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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aad142b4213817b5b081bed97f17d7cc47df571c21d8086bc296c69e526ba4f5' 
  AND token = 'aYH1uYPa6Fc2okKBr5fENZ3avdWgAgdSSsBZC4CH0Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}