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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6263f58f4a8d65e94626e69e56798b0d002a2b402a3ccda2ec7285c5433fab2' 
  AND token = 'EwgRt+EL6lfHsITYcQHZtkcOmk7zYMvO0toFUbnY+4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}