SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a69729bc8d87a9b57181ce2410ecf08b40711306e6e364caafa7e1877f07c585' 
  AND token = 'DbQrZlw7Czx8+T2ixJlwvG26r8dXIv8+RwMHmQmj7ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}