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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809c6e0f1c6bb0e1b80a71211b20a5a1b421cedea7896dd64525f2379920c981' 
  AND token = 'LGKy7Oq9pFtACKNSeTiIucbilvxHmxXbn/aaIQBGsnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}