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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c402b2ec3eb36c5dff80317f7735e7df2f4c136b30961f07f1add344112398' 
  AND token = '5ZTQ4vcEnO4yxCzbDR/Oa5/bSgjoy8FO1ML8q9ghCdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}