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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d2f80980e0aa104d96dec3d804bb19943968baed18da9ba386cc6c29b72844' 
  AND token = 'VJ5G5OwHLelgR2wb0tcTOv8L62zMID5DKZ/kv/jP4S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}