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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9038b9efd0700e7b3f8341feaf141f54d1c210a854fb5f46fc7e08faa07a868' 
  AND token = '8+isPKdqDILbMnsIAexTDZ6L6CL4iSF0OzcAnWcRBVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}