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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6989bcf8f489728ce90843ab522a0f816b18243cb57d4c150afa29007b00eb80' 
  AND token = 'thuTYmy2jhg3hOL1lwp7gaQrCQXFwHc8gxbUZlUJAOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}