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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4536c09f108fde3c37c8ae78b0677084b9631de1f8b92266b8a737789ed3252a' 
  AND token = '8lX/p+TkLUwBGQen7NWWLxG2dh5/EAngwSzSQrY2daM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}