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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b1255e0841abd91ec64ac42d9c666fbb1b52bd39e91c6234fed0f9835f1d78' 
  AND token = 'fO/xAr1cFptGXplsMFfmD8y/rLLmDx9vpm5/dGMELA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}