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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56200317a87d5981473939e7e2dc0b626b739304dcc549d4cea65723f65144fd' 
  AND token = 'M9lR0PQFoeVfzf/dKMw+ADJ9LDaJlPLOxmd0JXiJrEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}