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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b052b076b49877fd612671df61dddb11e1fdbee6c619e6b9666ca365a9816940' 
  AND token = 'rblc1rbHDXPnPLD0nNyEI9UlAWUb1oX6+/zPPMcdjb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}