SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e894d466f4e33ddf40f91dac390fef41c60189c24112ea4950adade53ab0bdd6' 
  AND token = 'm1D7kCvkxzjdqHxJfa+5raXmHsY6BUrfKOtqrhwNyGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}