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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c9b72bb879e715c99c50b06c3ed051c7807b8a1af1053336f14c3a86340e0b' 
  AND token = 'FGqt6E66M6LjPHpiD1HMRp3McLosr1lKHQxWSHI6SA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}