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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a0bc2a5d5973fee562455f96654c2166238224358a34e40248b69572dc240f4' 
  AND token = '9pjE5mcwwm6jvUNBiMfVDkBMbDsdsOq3Kh1AJ2D8RBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}